Macrophage-mediated delivery of light activated nitric oxide prodrugs with spatial, temporal and concentration control

Nitric oxide (NO) holds great promise as a treatment for cancer hypoxia, if its concentration and localization can be precisely controlled. Here, we report a “Trojan Horse” strategy to provide the necessary spatial, temporal, and dosage control of such drug-delivery therapies at targeted tissues. De...

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Detalles Bibliográficos
Autores principales: Evans, Michael A., Huang, Po-Ju, Iwamoto, Yuji, Ibsen, Kelly N., Chan, Emory M., Hitomi, Yutaka, Ford, Peter C., Mitragotri, Samir
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Royal Society of Chemistry 2018
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5939611/
https://www.ncbi.nlm.nih.gov/pubmed/29780505
http://dx.doi.org/10.1039/c8sc00015h

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5939611/
https://www.ncbi.nlm.nih.gov/pubmed/29780505
http://dx.doi.org/10.1039/c8sc00015h

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