Cargando…

The carbon chain-selective adenylation enzyme TamA: the missing link between fatty acid and pyrrole natural product biosynthesis

The marine bacterium Pseudoalteromonas tunicata produces the bipyrrole antibiotic tambjamine YP1. This natural product is built from common amino acid and fatty acid building blocks in a biosynthetic pathway that is encoded in the tam operon which contains 19 genes. The exact role that each of these...

Descripción completa

Detalles Bibliográficos
Autores principales: Marchetti, Piera M., Kelly, Van, Simpson, Joanna P., Ward, Mairi, Campopiano, Dominic J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Royal Society of Chemistry 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5939613/
https://www.ncbi.nlm.nih.gov/pubmed/29594310
http://dx.doi.org/10.1039/c8ob00441b