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Iriomoteolides: novel chemical tools to study actin dynamics

Despite its promising biological profile, the cellular targets of iriomoteolide-3a, a novel 15-membered macrolide isolated from Amphidinium sp., have remained unknown. A small library of non-natural iriomoteolide-3a analogues is presented here as a result of a novel, highly convergent, catalysis-bas...

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Detalles Bibliográficos
Autores principales: Unzue, A., Cribiú, R., Hoffman, M. M., Knehans, T., Lafleur, K., Caflisch, A., Nevado, C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Royal Society of Chemistry 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5939837/
https://www.ncbi.nlm.nih.gov/pubmed/29780512
http://dx.doi.org/10.1039/c7sc04286h