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Oncolytic adenovirus Ad657 for systemic virotherapy against prostate cancer

BACKGROUND: Human species C adenovirus serotype 5 (Ad5) is the archetype oncolytic adenovirus and has been used in the vast majority of preclinical and clinical tests. While Ad5 can be robust, species C Ad6 has lower seroprevalence, side effects, and appears to be more potent as a systemic therapy a...

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Detalles Bibliográficos
Autores principales: Nguyen, Tien V, Crosby, Catherine M, Heller, Gregory J, Mendel, Zachary I, Barry, Mary E, Barry, Michael A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5939883/
https://www.ncbi.nlm.nih.gov/pubmed/29765912
http://dx.doi.org/10.2147/OV.S155946