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MYSM1 Is Essential for Maintaining Hematopoietic Stem Cell (HSC) Quiescence and Survival
BACKGROUND: Histone H2A deubiquitinase MYSM1 has recently been shown to be essential for hematopoiesis and hematopoietic stem cell (HSC) function in both mice and humans. However, conventional MYSM1 knockouts cause partial embryonic lethality and growth retardation, and it is difficult to convincing...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
International Scientific Literature, Inc.
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5939948/ https://www.ncbi.nlm.nih.gov/pubmed/29694335 http://dx.doi.org/10.12659/MSM.906876 |