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MYSM1 Is Essential for Maintaining Hematopoietic Stem Cell (HSC) Quiescence and Survival

BACKGROUND: Histone H2A deubiquitinase MYSM1 has recently been shown to be essential for hematopoiesis and hematopoietic stem cell (HSC) function in both mice and humans. However, conventional MYSM1 knockouts cause partial embryonic lethality and growth retardation, and it is difficult to convincing...

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Detalles Bibliográficos
Autores principales: Huo, Yi, Li, Bing-Yi, Lin, Zhi-Feng, Wang, Wei, Jiang, Xiao-Xia, Chen, Xu, Xi, Wen-Jin, Li, Yu-Fang, Yang, An-Gang, Chen, Si-Yi, Wang, Tao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Scientific Literature, Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5939948/
https://www.ncbi.nlm.nih.gov/pubmed/29694335
http://dx.doi.org/10.12659/MSM.906876