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Using de novo protein structure predictions to measure the quality of very large multiple sequence alignments

Motivation: Multiple sequence alignments (MSAs) with large numbers of sequences are now commonplace. However, current multiple alignment benchmarks are ill-suited for testing these types of alignments, as test cases either contain a very small number of sequences or are based purely on simulation ra...

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Detalles Bibliográficos
Autores principales: Fox, Gearóid, Sievers, Fabian, Higgins, Desmond G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5939968/
https://www.ncbi.nlm.nih.gov/pubmed/26568625
http://dx.doi.org/10.1093/bioinformatics/btv592