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Accurate estimation of isoelectric point of protein and peptide based on amino acid sequences

Motivation: In any macromolecular polyprotic system—for example protein, DNA or RNA—the isoelectric point—commonly referred to as the pI—can be defined as the point of singularity in a titration curve, corresponding to the solution pH value at which the net overall surface charge—and thus the electr...

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Detalles Bibliográficos
Autores principales: Audain, Enrique, Ramos, Yassel, Hermjakob, Henning, Flower, Darren R., Perez-Riverol, Yasset
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5939969/
https://www.ncbi.nlm.nih.gov/pubmed/26568629
http://dx.doi.org/10.1093/bioinformatics/btv674