Cargando…

Inducible Genome Editing with Conditional CRISPR/Cas9 Mice

Genetically engineered mouse models (GEMMs) are powerful tools by which to probe gene function in vivo, obtain insight into disease etiology, and identify modifiers of drug response. Increased sophistication of GEMMs has led to the design of tissue-specific and inducible models in which genes of int...

Descripción completa

Detalles Bibliográficos
Autores principales: Katigbak, Alexandra, Robert, Francis, Paquet, Marilène, Pelletier, Jerry
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Genetics Society of America 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5940154/
https://www.ncbi.nlm.nih.gov/pubmed/29519936
http://dx.doi.org/10.1534/g3.117.300327