Optimizing exosomal RNA isolation for RNA-Seq analyses of archival sera specimens

Exosomes are endosome-derived membrane vesicles that contain proteins, lipids, and nucleic acids. The exosomal transcriptome mediates intercellular communication, and represents an understudied reservoir of novel biomarkers for human diseases. Next-generation sequencing enables complex quantitative...

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Detalles Bibliográficos
Autores principales: Prendergast, Emily N., de Souza Fonseca, Marcos Abraão, Dezem, Felipe Segato, Lester, Jenny, Karlan, Beth Y., Noushmehr, Houtan, Lin, Xianzhi, Lawrenson, Kate
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5940186/
https://www.ncbi.nlm.nih.gov/pubmed/29738525
http://dx.doi.org/10.1371/journal.pone.0196913

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5940186/
https://www.ncbi.nlm.nih.gov/pubmed/29738525
http://dx.doi.org/10.1371/journal.pone.0196913

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