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Optimizing exosomal RNA isolation for RNA-Seq analyses of archival sera specimens
Exosomes are endosome-derived membrane vesicles that contain proteins, lipids, and nucleic acids. The exosomal transcriptome mediates intercellular communication, and represents an understudied reservoir of novel biomarkers for human diseases. Next-generation sequencing enables complex quantitative...
Autores principales: | Prendergast, Emily N., de Souza Fonseca, Marcos Abraão, Dezem, Felipe Segato, Lester, Jenny, Karlan, Beth Y., Noushmehr, Houtan, Lin, Xianzhi, Lawrenson, Kate |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5940186/ https://www.ncbi.nlm.nih.gov/pubmed/29738525 http://dx.doi.org/10.1371/journal.pone.0196913 |
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