The hypoxia inducible factor/erythropoietin (EPO)/EPO receptor pathway is disturbed in a rat model of chronic kidney disease related anemia

OBJECTIVES: Anemia is a known driver for hypoxia inducible factor (HIF) which leads to increased renal erythropoietin (EPO) synthesis. Bone marrow (BM) EPO receptor (EPOR) signals are transduced through a JAK2-STAT5 pathway. The origins of anemia of chronic kidney disease (CKD) are multifactorial, i...

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Detalles Bibliográficos
Autores principales: Landau, Daniel, London, Lital, Bandach, Inbar, Segev, Yael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5940200/
https://www.ncbi.nlm.nih.gov/pubmed/29738538
http://dx.doi.org/10.1371/journal.pone.0196684

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5940200/
https://www.ncbi.nlm.nih.gov/pubmed/29738538
http://dx.doi.org/10.1371/journal.pone.0196684

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