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BaiCD gene cluster abundance is negatively correlated with Clostridium difficile infection

BACKGROUND: Clostridium difficile infection (CDI) is a major cause of hospital-acquired diarrhea. Secondary bile acids were shown to confer resistance to colonization by C. difficile. 7α-dehydroxylation is a key step in transformation of primary to secondary bile acids and required genes have been l...

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Detalles Bibliográficos
Autores principales: Solbach, Philipp, Chhatwal, Patrick, Woltemate, Sabrina, Tacconelli, Evelina, Buhl, Michael, Gerhard, Markus, Thoeringer, Christoph K., Vehreschild, Maria J. G. T., Jazmati, Nathalie, Rupp, Jan, Manns, Michael P., Bachmann, Oliver, Suerbaum, Sebastian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5940204/
https://www.ncbi.nlm.nih.gov/pubmed/29738579
http://dx.doi.org/10.1371/journal.pone.0196977