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Correcting for batch effects in case-control microbiome studies

High-throughput data generation platforms, like mass-spectrometry, microarrays, and second-generation sequencing are susceptible to batch effects due to run-to-run variation in reagents, equipment, protocols, or personnel. Currently, batch correction methods are not commonly applied to microbiome se...

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Detalles Bibliográficos
Autores principales: Gibbons, Sean M., Duvallet, Claire, Alm, Eric J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5940237/
https://www.ncbi.nlm.nih.gov/pubmed/29684016
http://dx.doi.org/10.1371/journal.pcbi.1006102