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Effects of spatiotemporal HSV-2 lesion dynamics and antiviral treatment on the risk of HIV-1 acquisition

Patients with Herpes Simplex Virus-2 (HSV-2) infection face a significantly higher risk of contracting HIV-1. This is thought to be due to herpetic lesions serving as entry points for HIV-1 and tissue-resident CD4+ T cell counts increasing during HSV-2 lesional events. We have created a stochastic a...

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Detalles Bibliográficos
Autores principales: Byrne, Catherine M., Gantt, Soren, Coombs, Daniel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5940244/
https://www.ncbi.nlm.nih.gov/pubmed/29698393
http://dx.doi.org/10.1371/journal.pcbi.1006129