Interferon induced protein 35 exacerbates H5N1 influenza disease through the expression of IL-12p40 homodimer

Pro-inflammatory cytokinemia is a hallmark of highly pathogenic H5N1 influenza virus (IAV) disease yet little is known about the role of host proteins in modulating a pathogenic innate immune response. The host Interferon Induced Protein 35 (Ifi35) has been implicated in increased susceptibility to...

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Detalles Bibliográficos
Autores principales: Gounder, Anshu P., Yokoyama, Christine C., Jarjour, Nicholas N., Bricker, Traci L., Edelson, Brian T., Boon, Adrianus C. M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5940246/
https://www.ncbi.nlm.nih.gov/pubmed/29698474
http://dx.doi.org/10.1371/journal.ppat.1007001

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5940246/
https://www.ncbi.nlm.nih.gov/pubmed/29698474
http://dx.doi.org/10.1371/journal.ppat.1007001

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