Atom-by-atom tuning of the electrostatic potassium-channel modulator dehydroabietic acid

Dehydroabietic acid (DHAA) is a naturally occurring component of pine resin that was recently shown to open voltage-gated potassium (K(V)) channels. The hydrophobic part of DHAA anchors the compound near the channel’s positively charged voltage sensor in a pocket between the channel and the lipid me...

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Detalles Bibliográficos
Autores principales: Silverå Ejneby, Malin, Wu, Xiongyu, Ottosson, Nina E., Münger, E. Peter, Lundström, Ingemar, Konradsson, Peter, Elinder, Fredrik
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2018
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5940250/
https://www.ncbi.nlm.nih.gov/pubmed/29626041
http://dx.doi.org/10.1085/jgp.201711965

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5940250/
https://www.ncbi.nlm.nih.gov/pubmed/29626041
http://dx.doi.org/10.1085/jgp.201711965

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