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Cryo-electron microscopy structures and progress toward a dynamic understanding of K(ATP) channels

Adenosine triphosphate (ATP)–sensitive K(+) (K(ATP)) channels are molecular sensors of cell metabolism. These hetero-octameric channels, comprising four inward rectifier K(+) channel subunits (Kir6.1 or Kir6.2) and four sulfonylurea receptor (SUR1 or SUR2A/B) subunits, detect metabolic changes via t...

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Detalles Bibliográficos
Autor principal: Puljung, Michael C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5940251/
https://www.ncbi.nlm.nih.gov/pubmed/29685928
http://dx.doi.org/10.1085/jgp.201711978