Microbial symbionts regulate the primary Ig repertoire

The ability of immunoglobulin (Ig) to recognize pathogens is critical for optimal immune fitness. Early events that shape preimmune Ig repertoires, expressed on IgM(+) IgD(+) B cells as B cell receptors (BCRs), are poorly defined. Here, we studied germ-free mice and conventionalized littermates to e...

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Detalles Bibliográficos
Autores principales: Chen, Yuezhou, Chaudhary, Neha, Yang, Nicole, Granato, Alessandra, Turner, Jacob A., Howard, Shannon L., Devereaux, Colby, Zuo, Teng, Shrestha, Akritee, Goel, Rishi R., Neuberg, Donna, Wesemann, Duane R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2018
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5940265/
https://www.ncbi.nlm.nih.gov/pubmed/29588346
http://dx.doi.org/10.1084/jem.20171761

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5940265/
https://www.ncbi.nlm.nih.gov/pubmed/29588346
http://dx.doi.org/10.1084/jem.20171761

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