Uhrf1 regulates germinal center B cell expansion and affinity maturation to control viral infection

The production of high-affinity antibody is essential for pathogen clearance. Antibody affinity is increased through germinal center (GC) affinity maturation, which relies on BCR somatic hypermutation (SHM) followed by antigen-based selection. GC B cell proliferation is essentially involved in these...

Descripción completa

Detalles Bibliográficos
Autores principales: Chen, Chao, Zhai, Sulan, Zhang, Le, Chen, Jingjing, Long, Xuehui, Qin, Jun, Li, Jianhua, Huo, Ran, Wang, Xiaoming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2018
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5940267/
https://www.ncbi.nlm.nih.gov/pubmed/29618490
http://dx.doi.org/10.1084/jem.20171815

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5940267/
https://www.ncbi.nlm.nih.gov/pubmed/29618490
http://dx.doi.org/10.1084/jem.20171815

Ejemplares similares