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Uhrf1 regulates germinal center B cell expansion and affinity maturation to control viral infection

The production of high-affinity antibody is essential for pathogen clearance. Antibody affinity is increased through germinal center (GC) affinity maturation, which relies on BCR somatic hypermutation (SHM) followed by antigen-based selection. GC B cell proliferation is essentially involved in these...

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Detalles Bibliográficos
Autores principales:	Chen, Chao, Zhai, Sulan, Zhang, Le, Chen, Jingjing, Long, Xuehui, Qin, Jun, Li, Jianhua, Huo, Ran, Wang, Xiaoming
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Rockefeller University Press 2018
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5940267/ https://www.ncbi.nlm.nih.gov/pubmed/29618490 http://dx.doi.org/10.1084/jem.20171815

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