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CLAMP/Spef1 regulates planar cell polarity signaling and asymmetric microtubule accumulation in the Xenopus ciliated epithelia

Most epithelial cells polarize along the axis of the tissue, a feature known as planar cell polarity (PCP). The initiation of PCP requires cell–cell signaling via the noncanonical Wnt/PCP pathway. Additionally, changes in the cytoskeleton both facilitate and reflect this polarity. We have identified...

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Detalles Bibliográficos
Autores principales: Kim, Sun K., Zhang, Siwei, Werner, Michael E., Brotslaw, Eva J., Mitchell, Jennifer W., Altabbaa, Mohamed M., Mitchell, Brian J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5940297/
https://www.ncbi.nlm.nih.gov/pubmed/29514918
http://dx.doi.org/10.1083/jcb.201706058