BBSome trains remove activated GPCRs from cilia by enabling passage through the transition zone

A diffusion barrier at the transition zone enables the compartmentalization of signaling molecules by cilia. The BBSome and the small guanosine triphosphatase Arl6, which triggers BBSome coat polymerization, are required for the exit of activated signaling receptors from cilia, but how diffusion bar...

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Detalles Bibliográficos
Autores principales: Ye, Fan, Nager, Andrew R., Nachury, Maxence V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2018
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5940304/
https://www.ncbi.nlm.nih.gov/pubmed/29483145
http://dx.doi.org/10.1083/jcb.201709041

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5940304/
https://www.ncbi.nlm.nih.gov/pubmed/29483145
http://dx.doi.org/10.1083/jcb.201709041

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