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Cell size–dependent regulation of Wee1 localization by Cdr2 cortical nodes

Cell size control requires mechanisms that link cell growth with Cdk1 activity. In fission yeast, the protein kinase Cdr2 forms cortical nodes that include the Cdk1 inhibitor Wee1 along with the Wee1-inhibitory kinase Cdr1. We investigated how nodes inhibit Wee1 during cell growth. Biochemical fract...

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Detalles Bibliográficos
Autores principales: Allard, Corey A.H., Opalko, Hannah E., Liu, Ko-Wei, Medoh, Uche, Moseley, James B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5940308/
https://www.ncbi.nlm.nih.gov/pubmed/29514920
http://dx.doi.org/10.1083/jcb.201709171