Basal mitophagy is widespread in Drosophila but minimally affected by loss of Pink1 or parkin

The Parkinson’s disease factors PINK1 and parkin are strongly implicated in stress-induced mitophagy in vitro, but little is known about their impact on basal mitophagy in vivo. We generated transgenic Drosophila melanogaster expressing fluorescent mitophagy reporters to evaluate the impact of Pink1...

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Detalles Bibliográficos
Autores principales: Lee, Juliette J., Sanchez-Martinez, Alvaro, Zarate, Aitor Martinez, Benincá, Cristiane, Mayor, Ugo, Clague, Michael J., Whitworth, Alexander J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2018
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5940313/
https://www.ncbi.nlm.nih.gov/pubmed/29500189
http://dx.doi.org/10.1083/jcb.201801044

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5940313/
https://www.ncbi.nlm.nih.gov/pubmed/29500189
http://dx.doi.org/10.1083/jcb.201801044

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