Rerouting the Pathway for the Biosynthesis of the Side Ring System of Nosiheptide: The Roles of NosI, NosJ, and NosK

[Image: see text] Nosiheptide (NOS) is a highly modified thiopeptide antibiotic that displays formidable in vitro activity against a variety of Gram-positive bacteria. In addition to a central hydroxypyridine ring, NOS contains several other modifications, including multiple thiazole rings, dehydro-...

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Detalles Bibliográficos
Autores principales: Badding, Edward D., Grove, Tyler L., Gadsby, Lauren K., LaMattina, Joseph W., Boal, Amie K., Booker, Squire J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2017
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5940322/
https://www.ncbi.nlm.nih.gov/pubmed/28343381
http://dx.doi.org/10.1021/jacs.7b01497

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5940322/
https://www.ncbi.nlm.nih.gov/pubmed/28343381
http://dx.doi.org/10.1021/jacs.7b01497

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