The deubiquitinase USP9X promotes tumor cell survival and confers chemoresistance through YAP1 stabilization

The Yes-associated protein 1 (YAP1), a major downstream effector of the Hippo pathway, functions as a transcriptional regulator and plays an important role in cellular control of organ size and tumor growth. Elevated oncogenic activity of YAP1 has been clarified in different types of human cancers,...

Descripción completa

Detalles Bibliográficos
Autores principales: Li, Lei, Liu, Tongzheng, Li, Yunhui, Wu, Chenming, Luo, Kuntian, Yin, Yujiao, Chen, Yuping, Nowsheen, Somaira, Wu, Jinhuan, Lou, Zhenkun, Yuan, Jian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5940338/
https://www.ncbi.nlm.nih.gov/pubmed/29449692
http://dx.doi.org/10.1038/s41388-018-0134-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5940338/
https://www.ncbi.nlm.nih.gov/pubmed/29449692
http://dx.doi.org/10.1038/s41388-018-0134-2

Ejemplares similares