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The deubiquitinase USP9X promotes tumor cell survival and confers chemoresistance through YAP1 stabilization
The Yes-associated protein 1 (YAP1), a major downstream effector of the Hippo pathway, functions as a transcriptional regulator and plays an important role in cellular control of organ size and tumor growth. Elevated oncogenic activity of YAP1 has been clarified in different types of human cancers,...
| Autores principales: | , , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5940338/ https://www.ncbi.nlm.nih.gov/pubmed/29449692 http://dx.doi.org/10.1038/s41388-018-0134-2 |