Transformation of mouse T cells requires MYC and AKT activity in conjunction with inhibition of intrinsic apoptosis

Peripheral T-cell lymphoma is an aggressive non-Hodgkin's lymphoma characterized by excessive proliferation of transformed mature T cells. The number and nature of genetic aberrations required and sufficient for transformation of normal T cells into lymphomas is unknown. Here, using a combinato...

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Detalles Bibliográficos
Autores principales: Högstrand, Kari, Darmanin, Stephanie, Forshell, TachaZi Plym, Grandien, Alf
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2018
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5940390/
https://www.ncbi.nlm.nih.gov/pubmed/29765548
http://dx.doi.org/10.18632/oncotarget.25113

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5940390/
https://www.ncbi.nlm.nih.gov/pubmed/29765548
http://dx.doi.org/10.18632/oncotarget.25113

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