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Transformation of mouse T cells requires MYC and AKT activity in conjunction with inhibition of intrinsic apoptosis

Peripheral T-cell lymphoma is an aggressive non-Hodgkin's lymphoma characterized by excessive proliferation of transformed mature T cells. The number and nature of genetic aberrations required and sufficient for transformation of normal T cells into lymphomas is unknown. Here, using a combinato...

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Detalles Bibliográficos
Autores principales:	Högstrand, Kari, Darmanin, Stephanie, Forshell, TachaZi Plym, Grandien, Alf
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2018
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5940390/ https://www.ncbi.nlm.nih.gov/pubmed/29765548 http://dx.doi.org/10.18632/oncotarget.25113

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