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Comparison of infectivity and spread between HSV-1 and HSV-2 based oncolytic viruses on tumor cells with different receptor expression profiles

Herpes simplex virus (HSV) is one of the many viruses that have been modified or adapted for oncolytic purposes. There are two serotypes of HSV, HSV-1 and HSV-2. The majority of oncolytic HSVs, including T-VEC which has recently been approved by the US Food and Drug Administration (FDA) for clinical...

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Detalles Bibliográficos
Autores principales: Fu, Xinping, Tao, Lihua, Wang, Pin-Yi, Cripe, Timothy P., Zhang, Xiaoliu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5940406/
https://www.ncbi.nlm.nih.gov/pubmed/29765544
http://dx.doi.org/10.18632/oncotarget.25096