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Genetic alterations analysis in prognostic stratified groups identified TP53 and ARID1A as poor clinical performance markers in intrahepatic cholangiocarcinoma

The incidence and mortality rates of intrahepatic cholangiocarcinoma have been rising worldwide. Few patients present an early-stage disease that is amenable to curative surgery and after resection, high recurrence rates persist. To identify new independent marker related to aggressive behaviour, tw...

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Detalles Bibliográficos
Autores principales: Simbolo, Michele, Vicentini, Caterina, Ruzzenente, Andrea, Brunelli, Matteo, Conci, Simone, Fassan, Matteo, Mafficini, Andrea, Rusev, Borislav, Corbo, Vincenzo, Capelli, Paola, Bria, Emilio, Pedron, Serena, Turri, Giona, Lawlor, Rita T., Tortora, Giampaolo, Bassi, Claudio, Guglielmi, Alfredo, Scarpa, Aldo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5940669/
https://www.ncbi.nlm.nih.gov/pubmed/29740198
http://dx.doi.org/10.1038/s41598-018-25669-1