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Genetic alterations analysis in prognostic stratified groups identified TP53 and ARID1A as poor clinical performance markers in intrahepatic cholangiocarcinoma
The incidence and mortality rates of intrahepatic cholangiocarcinoma have been rising worldwide. Few patients present an early-stage disease that is amenable to curative surgery and after resection, high recurrence rates persist. To identify new independent marker related to aggressive behaviour, tw...
Autores principales: | Simbolo, Michele, Vicentini, Caterina, Ruzzenente, Andrea, Brunelli, Matteo, Conci, Simone, Fassan, Matteo, Mafficini, Andrea, Rusev, Borislav, Corbo, Vincenzo, Capelli, Paola, Bria, Emilio, Pedron, Serena, Turri, Giona, Lawlor, Rita T., Tortora, Giampaolo, Bassi, Claudio, Guglielmi, Alfredo, Scarpa, Aldo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5940669/ https://www.ncbi.nlm.nih.gov/pubmed/29740198 http://dx.doi.org/10.1038/s41598-018-25669-1 |
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