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Tracing the origin of heterogeneity and symmetry breaking in the early mammalian embryo

A fundamental question in developmental and stem cell biology concerns the origin and nature of signals that initiate asymmetry leading to pattern formation and self-organization. Instead of having prominent pre-patterning determinants as present in model organisms (worms, sea urchin, frog), we prop...

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Detalles Bibliográficos
Autores principales: Chen, Qi, Shi, Junchao, Tao, Yi, Zernicka-Goetz, Magdalena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5940674/
https://www.ncbi.nlm.nih.gov/pubmed/29739935
http://dx.doi.org/10.1038/s41467-018-04155-2