Can nitrocobalamin be reduced by ascorbic acid to nitroxylcobalamin? Some surprising mechanistic findings

ABSTRACT: Despite detailed studies on nitroxylcobalamin (CblNO) formation, the possible intracellular generation of CblNO via reduction of nitrocobalamin (CblNO(2)) remains questionable. To study this further, spectroscopic studies on the reaction of CblNO(2) with the intracellular antioxidant ascor...

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Detalles Bibliográficos
Autores principales: Polaczek, Justyna, Orzeł, Łukasz, Stochel, Grażyna, van Eldik, Rudi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2018
Materias:
Original Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5940710/
https://www.ncbi.nlm.nih.gov/pubmed/29435646
http://dx.doi.org/10.1007/s00775-018-1540-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5940710/
https://www.ncbi.nlm.nih.gov/pubmed/29435646
http://dx.doi.org/10.1007/s00775-018-1540-1

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