Differing Outcome of Experimental Autoimmune Encephalitis in Macrophage/Neutrophil- and T Cell-Specific gp130-Deficient Mice

gp130 cytokines are differentially involved in regulating the T helper (H) 17-driven pathogenesis of experimental autoimmune encephalomyelitis (EAE), the animal model of human multiple sclerosis. Interleukin (IL)-6 directly promotes the development of TH17 cells through the gp130/IL-6R complex. By c...

Descripción completa

Detalles Bibliográficos
Autores principales: Holz, Kristian, Prinz, Marco, Brendecke, Stefanie M., Hölscher, Alexandra, Deng, Fengyuan, Mitrücker, Hans-Willi, Rose-John, Stefan, Hölscher, Christoph
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5940746/
https://www.ncbi.nlm.nih.gov/pubmed/29770132
http://dx.doi.org/10.3389/fimmu.2018.00836

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5940746/
https://www.ncbi.nlm.nih.gov/pubmed/29770132
http://dx.doi.org/10.3389/fimmu.2018.00836

Ejemplares similares