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Differing Outcome of Experimental Autoimmune Encephalitis in Macrophage/Neutrophil- and T Cell-Specific gp130-Deficient Mice

gp130 cytokines are differentially involved in regulating the T helper (H) 17-driven pathogenesis of experimental autoimmune encephalomyelitis (EAE), the animal model of human multiple sclerosis. Interleukin (IL)-6 directly promotes the development of TH17 cells through the gp130/IL-6R complex. By c...

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Detalles Bibliográficos
Autores principales:	Holz, Kristian, Prinz, Marco, Brendecke, Stefanie M., Hölscher, Alexandra, Deng, Fengyuan, Mitrücker, Hans-Willi, Rose-John, Stefan, Hölscher, Christoph
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2018
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5940746/ https://www.ncbi.nlm.nih.gov/pubmed/29770132 http://dx.doi.org/10.3389/fimmu.2018.00836

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