Spermine Alleviates Acute Liver Injury by Inhibiting Liver-Resident Macrophage Pro-Inflammatory Response Through ATG5-Dependent Autophagy

Liver-resident macrophages (Kupffer cells, KCs) and autophagy play critical roles in the pathogenesis of toxin-induced liver injury. Recent evidence indicates that autophagy can regulate macrophage M1/M2 polarization under different inflammatory conditions. Polyamines, including putrescine, spermidi...

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Detalles Bibliográficos
Autores principales: Zhou, Shun, Gu, Jian, Liu, Rui, Wei, Song, Wang, Qi, Shen, Hongbing, Dai, Yifan, Zhou, Haoming, Zhang, Feng, Lu, Ling
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5940752/
https://www.ncbi.nlm.nih.gov/pubmed/29770139
http://dx.doi.org/10.3389/fimmu.2018.00948

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5940752/
https://www.ncbi.nlm.nih.gov/pubmed/29770139
http://dx.doi.org/10.3389/fimmu.2018.00948

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