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TRPV1 and the MCP-1/CCR2 Axis Modulate Post-UTI Chronic Pain

The etiology of chronic pelvic pain syndromes remains unknown. In a murine urinary tract infection (UTI) model, lipopolysaccharide of uropathogenic E. coli and its receptor TLR4 are required for post-UTI chronic pain development. However, downstream mechanisms of post-UTI chronic pelvic pain remain...

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Detalles Bibliográficos
Autores principales: Rosen, John M., Yaggie, Ryan E., Woida, Patrick J., Miller, Richard. J., Schaeffer, Anthony J., Klumpp, David J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5940763/
https://www.ncbi.nlm.nih.gov/pubmed/29739958
http://dx.doi.org/10.1038/s41598-018-24056-0