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Differential contributions of peripheral and central mechanisms to pain in a rodent model of osteoarthritis

The mechanisms underlying the transition from acute nociceptive pain to centrally maintained chronic pain are not clear. We have studied the contributions of the peripheral and central nervous systems during the development of osteoarthritis (OA) pain. Male Sprague-Dawley rats received unilateral in...

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Detalles Bibliográficos
Autores principales: Haywood, Adrian R., Hathway, Gareth J., Chapman, Victoria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5940779/
https://www.ncbi.nlm.nih.gov/pubmed/29740093
http://dx.doi.org/10.1038/s41598-018-25581-8