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Differential contributions of peripheral and central mechanisms to pain in a rodent model of osteoarthritis
The mechanisms underlying the transition from acute nociceptive pain to centrally maintained chronic pain are not clear. We have studied the contributions of the peripheral and central nervous systems during the development of osteoarthritis (OA) pain. Male Sprague-Dawley rats received unilateral in...
Autores principales: | Haywood, Adrian R., Hathway, Gareth J., Chapman, Victoria |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5940779/ https://www.ncbi.nlm.nih.gov/pubmed/29740093 http://dx.doi.org/10.1038/s41598-018-25581-8 |
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