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Synergistic combination of two antimicrobial agents closing each other’s mutant selection windows to prevent antimicrobial resistance
Antimicrobial resistance seriously threatened human health. Combination therapy is generally an effective strategy to fight resistance, while some data on its effects are conflicting. To explore the reasons, the fractional inhibitory concentration indexes (FICIs) of three designed combinations again...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5940791/ https://www.ncbi.nlm.nih.gov/pubmed/29740150 http://dx.doi.org/10.1038/s41598-018-25714-z |