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Networks of genetic similarity reveal non-neutral processes shape strain structure in Plasmodium falciparum
Pathogens compete for hosts through patterns of cross-protection conferred by immune responses to antigens. In Plasmodium falciparum malaria, the var multigene family encoding for the major blood-stage antigen PfEMP1 has evolved enormous genetic diversity through ectopic recombination and mutation....
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5940794/ https://www.ncbi.nlm.nih.gov/pubmed/29739937 http://dx.doi.org/10.1038/s41467-018-04219-3 |