The mechanical microenvironment regulates ovarian cancer cell morphology, migration, and spheroid disaggregation

There is growing appreciation of the importance of the mechanical properties of the tumor microenvironment on disease progression. However, the role of extracellular matrix (ECM) stiffness and cellular mechanotransduction in epithelial ovarian cancer (EOC) is largely unknown. Here, we investigated t...

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Detalles Bibliográficos
Autores principales: McKenzie, Andrew J., Hicks, Stephanie R., Svec, Kathryn V., Naughton, Hannah, Edmunds, Zöe L., Howe, Alan K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5940803/
https://www.ncbi.nlm.nih.gov/pubmed/29740072
http://dx.doi.org/10.1038/s41598-018-25589-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5940803/
https://www.ncbi.nlm.nih.gov/pubmed/29740072
http://dx.doi.org/10.1038/s41598-018-25589-0

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