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The mechanical microenvironment regulates ovarian cancer cell morphology, migration, and spheroid disaggregation
There is growing appreciation of the importance of the mechanical properties of the tumor microenvironment on disease progression. However, the role of extracellular matrix (ECM) stiffness and cellular mechanotransduction in epithelial ovarian cancer (EOC) is largely unknown. Here, we investigated t...
Autores principales: | McKenzie, Andrew J., Hicks, Stephanie R., Svec, Kathryn V., Naughton, Hannah, Edmunds, Zöe L., Howe, Alan K. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5940803/ https://www.ncbi.nlm.nih.gov/pubmed/29740072 http://dx.doi.org/10.1038/s41598-018-25589-0 |
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