Mammary fibroblasts reduce apoptosis and speed estrogen-induced hyperplasia in an organotypic MCF7-derived duct model

The estrogen receptor (ER) regulates the survival and growth of breast cancer cells, but it is less clear how components of the tissue microenvironment affect ER-mediated responses. We set out to test how human mammary fibroblasts (HMFs) modulate ER signaling and downstream cellular responses. We ex...

Descripción completa

Detalles Bibliográficos
Autores principales: Morgan, Molly M., Livingston, Megan K., Warrick, Jay W., Stanek, Eli M., Alarid, Elaine T., Beebe, David J., Johnson, Brian P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5940820/
https://www.ncbi.nlm.nih.gov/pubmed/29740030
http://dx.doi.org/10.1038/s41598-018-25461-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5940820/
https://www.ncbi.nlm.nih.gov/pubmed/29740030
http://dx.doi.org/10.1038/s41598-018-25461-1

Ejemplares similares