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Analysis of β-tubulin-carbendazim interaction reveals that binding site for MBC fungicides does not include residues involved in fungicide resistance

Methyl benzimidazole carbamate (MBC) fungicides are fungicidal compounds that exert their biological activities by preventing cell division through the inhibition of tubulin polymerization, which is the major component of microtubules. Several mutations in the β-tubulin gene contribute to MBC resist...

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Detalles Bibliográficos
Autores principales: Vela-Corcía, David, Romero, Diego, de Vicente, Antonio, Pérez-García, Alejandro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5940828/
https://www.ncbi.nlm.nih.gov/pubmed/29740047
http://dx.doi.org/10.1038/s41598-018-25336-5