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Overexpression of Cx43 in cells of the myocardial scar: Correction of post-infarct arrhythmias through heterotypic cell-cell coupling

Ventricular tachycardia (VT) is the most common and potentially lethal complication following myocardial infarction (MI). Biological correction of the conduction inhomogeneity that underlies re-entry could be a major advance in infarction therapy. As minimal increases in conduction of infarcted tiss...

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Detalles Bibliográficos
Autores principales: Roell, Wilhelm, Klein, Alexandra M., Breitbach, Martin, Becker, Torsten S., Parikh, Ashish, Lee, Jane, Zimmermann, Katrin, Reining, Shaun, Gabris, Beth, Ottersbach, Annika, Doran, Robert, Engelbrecht, Britta, Schiffer, Miriam, Kimura, Kenichi, Freitag, Patricia, Carls, Esther, Geisen, Caroline, Duerr, Georg D., Sasse, Philipp, Welz, Armin, Pfeifer, Alexander, Salama, Guy, Kotlikoff, Michael, Fleischmann, Bernd K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5940892/
https://www.ncbi.nlm.nih.gov/pubmed/29739982
http://dx.doi.org/10.1038/s41598-018-25147-8