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Exploration of genetic basis underlying individual differences in radiosensitivity within human populations using genome editing technology

DNA double-strand breaks (DSBs) induced by ionizing radiation (IR) are the initial and critical step in major alteration of genetic information and cell death. To prevent deleterious effects, DNA repair systems recognize and re-join DNA DSBs in human cells. It has been suggested that there are indiv...

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Detalles Bibliográficos
Autores principales: Miyamoto, Tatsuo, Akutsu, Silvia Natsuko, Tauchi, Hiroshi, Kudo, Yoshiki, Tashiro, Satoshi, Yamamoto, Takashi, Matsuura, Shinya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5941146/
https://www.ncbi.nlm.nih.gov/pubmed/29528422
http://dx.doi.org/10.1093/jrr/rry007