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Exploration of genetic basis underlying individual differences in radiosensitivity within human populations using genome editing technology
DNA double-strand breaks (DSBs) induced by ionizing radiation (IR) are the initial and critical step in major alteration of genetic information and cell death. To prevent deleterious effects, DNA repair systems recognize and re-join DNA DSBs in human cells. It has been suggested that there are indiv...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5941146/ https://www.ncbi.nlm.nih.gov/pubmed/29528422 http://dx.doi.org/10.1093/jrr/rry007 |