Cellular responses and gene expression profiles of colonic Lgr5(+) stem cells after low-dose/low-dose-rate radiation exposure

We previously found that high-dose-rate radiation induced a replenishment of the colonic Lgr5(+) stem cell pool, whereas low-dose-rate radiation did not. To identify key molecules that determine the dose-rate effects on this stem cell pool, we harvested colonic Lgr5(+) stem cells by cell sorting at...

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Detalles Bibliográficos
Autores principales: Otsuka, Kensuke, Suzuki, Keiji, Fujimichi, Yuki, Tomita, Masanori, Iwasaki, Toshiyasu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
Supplement Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5941159/
https://www.ncbi.nlm.nih.gov/pubmed/29281035
http://dx.doi.org/10.1093/jrr/rrx078

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5941159/
https://www.ncbi.nlm.nih.gov/pubmed/29281035
http://dx.doi.org/10.1093/jrr/rrx078

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