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Cellular responses and gene expression profiles of colonic Lgr5(+) stem cells after low-dose/low-dose-rate radiation exposure
We previously found that high-dose-rate radiation induced a replenishment of the colonic Lgr5(+) stem cell pool, whereas low-dose-rate radiation did not. To identify key molecules that determine the dose-rate effects on this stem cell pool, we harvested colonic Lgr5(+) stem cells by cell sorting at...
Autores principales: | Otsuka, Kensuke, Suzuki, Keiji, Fujimichi, Yuki, Tomita, Masanori, Iwasaki, Toshiyasu |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5941159/ https://www.ncbi.nlm.nih.gov/pubmed/29281035 http://dx.doi.org/10.1093/jrr/rrx078 |
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